Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety
The Journal of Antibiotics advance online publication, July 5 2017. doi:10.1038/ja.2017.59
Authors: Ko Kumura, Yoshinari Wakiyama, Kazutaka Ueda, Eijiro Umemura, Takashi Watanabe, Mikio Yamamoto, Takuji Yoshida & Keiichi Ajito
A brief history of antibiotics and select advances in their synthesis
The Journal of Antibiotics advance online publication, July 5 2017. doi:10.1038/ja.2017.62
Authors: Kyriacos C Nicolaou & Stephan Rigol
Effect of the meropenem MIC on the killing activity of meropenem and polymyxin B in combination against KPC-producing Klebsiella pneumoniae
The Journal of Antibiotics advance online publication, July 5 2017. doi:10.1038/ja.2017.73
Authors: Brandon Kulengowski, Jeffrey J Campion, David J Feola & David S Burgess
Allantopyrone A interferes with multiple components of the TNF receptor 1 complex and blocks RIP1 modifications in the TNF-α-induced signaling pathway
The Journal of Antibiotics advance online publication, July 5 2017. doi:10.1038/ja.2017.74
Authors: Hue Tu Quach, Riho Tanigaki, Junpei Yokoigawa, Yuriko Yamada, Masamitsu Niwa, Seiya Hirano, Yoshihito Shiono, Ken-ichi Kimura & Takao Kataoka
Trichopeptides A and B, trichocyclodipeptides A–C, new peptides from the ascomycete fungus Stagonospora trichophoricola
The Journal of Antibiotics advance online publication, July 5 2017. doi:10.1038/ja.2017.76
Authors: Zhengkun Chen, Xiuli Xu, Jinwei Ren, Wenzhao Wang, Xingzhong Liu & Erwei Li
Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety
The Journal of Antibiotics advance online publication, July 5 2017. doi:10.1038/ja.2017.77
Authors: Hiroyasu Ando, Aoi Kimishima, Motoyoshi Ohara, Tomoyasu Hirose, Takanori Matsumaru, Hirokazu Takada, Keisuke Morodome, Takehiro Miyamoto, Akihiro Sugawara, Satoshi Ōmura & Toshiaki Sunazuka
Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity
The Journal of Antibiotics advance online publication, June 28 2017. doi:10.1038/ja.2017.60
Authors: Yoshiaki Takahashi, Eijiro Umemura, Yoshihiko Kobayashi, Shoichi Murakami, Toru Nawa, Akihiro Morinaka, Toshiaki Miyake & Masakatsu Shibasaki
A 2,4′-linked tetrahydroxanthone dimer with protein tyrosine phosphatase 1B inhibitory activity from the Okinawan freshwater Aspergillus sp.
The Journal of Antibiotics advance online publication, June 28 2017. doi:10.1038/ja.2017.72
Authors: Henki Rotinsulu, Hiroyuki Yamazaki, Tomohito Miura, Satomi Chiba, Defny S Wewengkang, Deiske A Sumilat & Michio Namikoshi
Antimicrobial sulfonamides clear latent Kaposi sarcoma herpesvirus infection and impair MDM2–p53 complex formation
The Journal of Antibiotics advance online publication, June 14 2017. doi:10.1038/ja.2017.67
Authors: Fabrizio Angius, Enrica Piras, Sabrina Uda, Clelia Madeddu, Roberto Serpe, Rachele Bigi, Wuguo Chen, Dirk P Dittmer, Raffaello Pompei & Angela Ingianni
A three-component coupling approach to the ACE-ring substructure of C19-diterpene alkaloids
The Journal of Antibiotics advance online publication, June 14 2017. doi:10.1038/ja.2017.69
Authors: Kosuke Minagawa, Daisuke Urabe & Masayuki Inoue
A novel polycyclic meroterpenoid with aldose reductase inhibitory activity from medicinal mushroom Ganoderma leucocontextum
The Journal of Antibiotics advance online publication, May 24 2017. doi:10.1038/ja.2017.57
Authors: Jinjin Zhang, Ke Ma, Hongyu Chen, Kai Wang, Weiping Xiong, Li Bao & Hongwei Liu
Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid
The Journal of Antibiotics advance online publication, May 3 2017. doi:10.1038/ja.2017.49
Authors: Maria Falzone, Emmanuel Crespo, Klarissa Jones, Gulaba Khan, Victoria L Korn, Amreen Patel, Mira Patel, Krishnaben Patel, Carrie Perkins, Sana Siddiqui, Drew Stenger, Eileen Yu, Michael Gelber, Robert Scheffler, Vasyl Nayda, Ariela Ravin, Ronica Komal, Jeffrey D Rudolf, Ben Shen, Vincent Gullo & Arnold L Demain
New chlorinated xanthone and anthraquinone produced by a mangrove-derived fungus Penicillium citrinum HL-5126
The Journal of Antibiotics advance online publication, May 3 2017. doi:10.1038/ja.2017.52
Authors: Ke-Yao He, Cheng Zhang, Yi-Ru Duan, Guo-Lei Huang, Chun-Yan Yang, Xing-Rui Lu, Cai-Juan Zheng & Guang-Ying Chen
Synthesis and biological evaluation of indole core-based derivatives with potent antibacterial activity against resistant bacterial pathogens
The Journal of Antibiotics advance online publication, May 3 2017. doi:10.1038/ja.2017.55
Authors: Wei Hong, Jingyang Li, Zhe Chang, Xiaoli Tan, Hao Yang, Yifan Ouyang, Yanhui Yang, Sargit Kaur, Ian C Paterson, Yun Fong Ngeow & Hao Wang
Sonochemical synthesis of pyrido[2,3-d:6,5-d′]-dipyrimidines catalyzed by [HNMP]+[HSO4]− and their antimicrobial activity studies
The Journal of Antibiotics advance online publication, April 26 2017. doi:10.1038/ja.2017.47
Authors: Hossein Naeimi, Asieh Didar, Zahra Rashid & Zohreh Zahraie
Novel antibiotic screening methods to awaken silent or cryptic secondary metabolic pathways in actinomycetes
The Journal of Antibiotics advance online publication, April 26 2017. doi:10.1038/ja.2017.51
Author: Hiroyasu Onaka
Unique prostate cancer-toxic polyketides from marine sediment-derived fungus Isaria felina
The Journal of Antibiotics advance online publication, April 26 2017. doi:10.1038/ja.2017.53
Authors: Olga F Smetanina, Anton N Yurchenko, Elena V Ivanets, Anatoly I Kalinovsky, Yuliya V Khudyakova, Sergey A Dyshlovoy, Gunhild von Amsberg, Ekaterina A Yurchenko & Shamil Sh Afiyatullov
Verification of oligomycin A structure: synthesis and biological evaluation of 33-dehydrooligomycin A
The Journal of Antibiotics advance online publication, April 19 2017. doi:10.1038/ja.2017.48
Authors: Lyudmila N Lysenkova, Oleg Y Saveljev, Natalya E Grammatikova, Vladimir B Tsvetkov, Olga B Bekker, Valery N Danilenko, Lyubov G Dezhenkova, Eugene E Bykov, Olga A Omelchuk, Alexander M Korolev & Andrey E Shchekotikhin
Aurachin SS, a new antibiotic from Streptomyces sp. NA04227
The Journal of Antibiotics advance online publication, April 19 2017. doi:10.1038/ja.2017.50
Authors: Mei Zhang, Cheng Long Yang, Yong Sheng Xiao, Bo Zhang, Xin Zhao Deng, L i Yang, Jing Shi, Y i Shuang Wang, Wei Li, Rui Hua Jiao, Ren Xiang Tan & Hui Ming Ge
Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli
The Journal of Antibiotics advance online publication, April 12 2017. doi:10.1038/ja.2017.38
Authors: Gergana A Vandova, Robert V O'Brien, Brian Lowry, Thomas F Robbins, Curt R Fischer, Ronald W Davis, Chaitan Khosla, Colin JB Harvey & Maureen E Hillenmeyer
