Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity
The Journal of Antibiotics advance online publication, June 28 2017. doi:10.1038/ja.2017.60
Authors: Yoshiaki Takahashi, Eijiro Umemura, Yoshihiko Kobayashi, Shoichi Murakami, Toru Nawa, Akihiro Morinaka, Toshiaki Miyake & Masakatsu Shibasaki
A 2,4′-linked tetrahydroxanthone dimer with protein tyrosine phosphatase 1B inhibitory activity from the Okinawan freshwater Aspergillus sp.
The Journal of Antibiotics advance online publication, June 28 2017. doi:10.1038/ja.2017.72
Authors: Henki Rotinsulu, Hiroyuki Yamazaki, Tomohito Miura, Satomi Chiba, Defny S Wewengkang, Deiske A Sumilat & Michio Namikoshi
Antimicrobial sulfonamides clear latent Kaposi sarcoma herpesvirus infection and impair MDM2–p53 complex formation
The Journal of Antibiotics advance online publication, June 14 2017. doi:10.1038/ja.2017.67
Authors: Fabrizio Angius, Enrica Piras, Sabrina Uda, Clelia Madeddu, Roberto Serpe, Rachele Bigi, Wuguo Chen, Dirk P Dittmer, Raffaello Pompei & Angela Ingianni
A three-component coupling approach to the ACE-ring substructure of C19-diterpene alkaloids
The Journal of Antibiotics advance online publication, June 14 2017. doi:10.1038/ja.2017.69
Authors: Kosuke Minagawa, Daisuke Urabe & Masayuki Inoue
