Distribution and isolation of strains belonging to the order Solirubrobacterales
The Journal of Antibiotics advance online publication, July 1 2015. doi:10.1038/ja.2015.67
Authors: Tamae Seki, Atsuko Matsumoto, Satoshi Ōmura & Yōko Takahashi
Genome-based analysis of type-I polyketide synthase and nonribosomal peptide synthetase gene clusters in a novel strain taxonomically close to the genus Salinispora
The Journal of Antibiotics advance online publication, July 1 2015. doi:10.1038/ja.2015.69
Authors: Hisayuki Komaki, Tomohiko Tamura, Natsuko Ichikawa, Akio Oguchi, Moriyuki Hamada, Ken-ichiro Suzuki & Nobuyuki Fujita
Cytosine-type nucleosides from marine-derived Streptomyces rochei 06CM016
The Journal of Antibiotics advance online publication, July 1 2015. doi:10.1038/ja.2015.72
Authors: Semiha Çetinel Aksoy, Ataç Uzel & Erdal Bedir
An overproduction of astellolides induced by genetic disruption of chromatin-remodeling factors in Aspergillus oryzae
The Journal of Antibiotics advance online publication, July 1 2015. doi:10.1038/ja.2015.73
Authors: Yasutomo Shinohara, Makoto Kawatani, Yushi Futamura, Hiroyuki Osada & Yasuji Koyama
Development of a multiplex PCR system and its application in detection of blaSHV, blaTEM, blaCTX-M-1, blaCTX-M-9 and blaOXA-1 group genes in clinical Klebsiella pneumoniae and Escherichia coli strains
The Journal of Antibiotics advance online publication, June 24 2015. doi:10.1038/ja.2015.68
Authors: James O Ogutu, Qingmeng Zhang, Ying Huang, Huo Yan, Lijie Su, Bo Gao, Wenli Zhang, Jizi Zhao, Wenhui Cai, Wenjing Li, Hong Zhao, Yang Chen, Wuqi Song, Xiaobei Chen, Yingmei Fu & Fengmin Zhang
Xiakemycin A, a novel pyranonaphthoquinone antibiotic, produced by the Streptomyces sp. CC8-201 from the soil of a karst cave
The Journal of Antibiotics advance online publication, June 24 2015. doi:10.1038/ja.2015.70
Authors: Zhong-ke Jiang, Lin Guo, Chuan Chen, Shao-wei Liu, Lin Zhang, Su-juan Dai, Qi-yang He, Xue-fu You, Xin-xin Hu, Li Tuo, Wei Jiang & Cheng-hang Sun
We continue to be warned about the risk of antibiotic resistance. This campaign has targeted medicine and agriculture, asking these industries to pay attention to the risks of widespread resistance and to cut the use of antibiotics wherever possible. However, there has been little to no mention of the widespread use of antibiotics in the scientific research community. As scientists we use antibiotics and antibiotic resistance as fundamental tools for our research; almost all conventional plasmids use an antibiotic resistance gene as a selectable marker, offering us an easy method of screening. With molecular biology and genetics at the heart of many research disciplines, these tools are ubiquitous. Scientists have a responsibility to monitor and reduce our use of antibiotics. With the growth and fast advancement of synthetic biology, it is timely for us to consider other options and to teach the next generation of researchers by example how to truly value antibiotics by using them more responsibly.
