mardi 13 décembre 2016

New aminoglycoside-modifying enzymes APH(3′)-VIII and APH(3′)-IX in Acinetobacter rudis and Acinetobacter gerneri

New aminoglycoside-modifying enzymes APH(3′)-VIII and APH(3′)-IX in Acinetobacter rudis and Acinetobacter gerneri

The Journal of Antibiotics advance online publication, December 14 2016. doi:10.1038/ja.2016.144

Authors: Eun-Jeong Yoon, Catherine Grillot-Courvalin & Patrice Courvalin



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mardi 6 décembre 2016

Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives

Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives

The Journal of Antibiotics advance online publication, December 7 2016. doi:10.1038/ja.2016.139

Authors: Ko Kumura, Yoshinari Wakiyama, Kazutaka Ueda, Eijiro Umemura, Takashi Watanabe, Megumi Kumura, Takuji Yoshida & Keiichi Ajito



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Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance

Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance

The Journal of Antibiotics advance online publication, December 7 2016. doi:10.1038/ja.2016.141

Authors: Tomoyasu Hirose, Yasuhiro Kojima, Hidehito Matsui, Hideaki Hanaki, Masato Iwatsuki, Kazuro Shiomi, Satoshi Ōmura & Toshiaki Sunazuka



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mardi 29 novembre 2016

Nature nurtures the design of new semi-synthetic macrolide antibiotics

Nature nurtures the design of new semi-synthetic macrolide antibiotics

The Journal of Antibiotics advance online publication, November 30 2016. doi:10.1038/ja.2016.137

Authors: Prabhavathi Fernandes, Evan Martens & David Pereira



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Bacterial proteases, untapped antimicrobial drug targets

Bacterial proteases, untapped antimicrobial drug targets

The Journal of Antibiotics advance online publication, November 30 2016. doi:10.1038/ja.2016.138

Authors: Elizabeth Culp & Gerard D Wright



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Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of MSD-819 (6-chloro-2-quinoxalinecarboxylic acid 1,4-dioxide)

Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of MSD-819 (6-chloro-2-quinoxalinecarboxylic acid 1,4-dioxide)

The Journal of Antibiotics advance online publication, November 30 2016. doi:10.1038/ja.2016.140

Authors: Nicola Ooi & Alex J O'Neill



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Quinoline and naphthalene derivatives from Saccharopolyspora sp. YIM M13568

Quinoline and naphthalene derivatives from Saccharopolyspora sp. YIM M13568

The Journal of Antibiotics advance online publication, November 30 2016. doi:10.1038/ja.2016.142

Authors: Mingwei Sun, Jinhuan Ou, Wenjun Li & Chunhua Lu



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